{"id":8752,"date":"2021-02-02T12:54:26","date_gmt":"2021-02-02T01:54:26","guid":{"rendered":"https:\/\/scienceillustrated.com.au\/blog\/?p=8752"},"modified":"2021-02-02T12:54:26","modified_gmt":"2021-02-02T01:54:26","slug":"aussie-lungfish-has-largest-animal-genome-known-to-science","status":"publish","type":"post","link":"https:\/\/scienceillustrated.com.au\/blog\/nature\/animals\/aussie-lungfish-has-largest-animal-genome-known-to-science\/","title":{"rendered":"Aussie lungfish has largest animal genome known to science"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-8753\" src=\"https:\/\/scienceillustrated.com.au\/blog\/wp-content\/uploads\/2021\/02\/csm__c_schedl_IMP-Lungfish3_aa9c0458ba.jpg\" alt=\"IMP\/L.Schedl\" width=\"1472\" height=\"800\" srcset=\"https:\/\/scienceillustrated.com.au\/blog\/wp-content\/uploads\/2021\/02\/csm__c_schedl_IMP-Lungfish3_aa9c0458ba.jpg 1472w, https:\/\/scienceillustrated.com.au\/blog\/wp-content\/uploads\/2021\/02\/csm__c_schedl_IMP-Lungfish3_aa9c0458ba-300x163.jpg 300w, https:\/\/scienceillustrated.com.au\/blog\/wp-content\/uploads\/2021\/02\/csm__c_schedl_IMP-Lungfish3_aa9c0458ba-1024x557.jpg 1024w, https:\/\/scienceillustrated.com.au\/blog\/wp-content\/uploads\/2021\/02\/csm__c_schedl_IMP-Lungfish3_aa9c0458ba-768x417.jpg 768w\" sizes=\"(max-width: 1472px) 100vw, 1472px\" \/><\/p>\n<p class=\"p1\"><span class=\"s1\"><b>Scientists are teasing out the secrets that place the Australian lungfish near a critical moment of evolution.<\/b><\/span><\/p>\n<p class=\"p1\"><span class=\"s3\"><b>A team of researchers at the Research Institute of Molecular Pathology (IMP) in Vienna has sequenced the genome of the Australian lungfish for the first time, unveiling striking similarities to land-dwelling vertebrates. The study, published in <em>Nature<\/em> this January, also sets a record for the largest animal genome ever sequenced at 43 billion base pairs, 14 times the length of the human genome.<\/b><\/span><\/p>\n<p class=\"p2\"><span class=\"s3\"><b>The Australian lungfish is an endangered air-breathing fish with a body resembling a cross between a fish and a newt, and it is one of the few living relatives of the first fish to crawl out of the water to colonise land some 380 million years ago. The unveiled genome sequence settles a longstanding debate as to whether lungfish or coelacanths \u2013 another group of archaic fish with lobed fins \u2013 were more closely related to amphibians, reptiles, birds, and mammals. This study provides unequivocal evidence that coelacanths diverged first, while lungfish branched off from the line leading to four-legged animals only 420 million years ago. <\/b><\/span><\/p>\n<p class=\"p2\"><span class=\"s3\"><b>The IMP scientists also investigated gene expression in various tissues. The new genome highlights similarities between lungfish and land vertebrates: for example, the number and expression levels of genes associated with lung development and articulated limbs, also the detection of air-borne smells, are closer to those of amphibians than other fish.<\/b><\/span><\/p>\n<p class=\"p2\"><span class=\"s3\"><b>\u201cThere is no doubt that the newly sequenced genome will unveil more of the secrets of this bizarre vertebrate in the future,\u201d says Elly Tanaka, Group Leader at the IMP. \u201cNot only can it teach us things about adaptations to life on land, but it may also explain how certain genomes evolve to be so big.\u201d<\/b><\/span><\/p>\n<p class=\"p2\"><span class=\"s3\"><b>While 43 billion base pairs beats out all previous animal contenders, some plants have even longer genomes. The Japanese flowering plant Paris japonica has 150 billion base pairs of DNA per cell.<\/b><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists are teasing out the secrets that place the Australian lungfish near a critical moment of evolution. A team of researchers at the Research Institute of Molecular Pathology (IMP) in Vienna has sequenced&#8230;<\/p>\n","protected":false},"author":15,"featured_media":8753,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,98,88,25,32,23],"tags":[867,162,923,922],"class_list":["post-8752","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-animals","category-biology","category-genetics","category-marine-australia","category-marine-biology","category-science-update","tag-evolution","tag-genetics-2","tag-longest-genome","tag-lungfish"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/posts\/8752"}],"collection":[{"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/comments?post=8752"}],"version-history":[{"count":1,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/posts\/8752\/revisions"}],"predecessor-version":[{"id":8754,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/posts\/8752\/revisions\/8754"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/media\/8753"}],"wp:attachment":[{"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/media?parent=8752"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/categories?post=8752"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceillustrated.com.au\/blog\/wp-json\/wp\/v2\/tags?post=8752"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}